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USMLE Vault · Step 1 · Neurology

Neurology, start to finish, in 7 days

System 10 of 11, right before cardio. For IMGs who opened neuro once and closed it again.

68 First Aid pages31 organisms4 drug groups291 MCQs7 days

By Dr. Marish Asudani · Published

How do I study neurology for Step 1?

Do not start neurology early. Finish genetics, MSK, psychiatry and ANS first. Then 7 days: the 31 organisms and neuro drugs, active reading of First Aid pp. 500–569 with the MCQs (skip the ear pages, 547–548), the Mehlman neuro playlist, the FA Foundation Anki neuro deck, then UWorld neuro.

Read this first

This is only for you if you have roughly 10–12 hours a day for studying, and you're an intern or a graduate.

Working, or studying 5–8 hours a day? Keep the same order and stretch the days. Step 1 while working →

Neurology breaks people because they open it too early. CNS leans on almost everything before it: genetics, neurotransmitters, the autonomic drugs, psychiatry. Start it cold and every page feels like 3 subjects at once.

So this page has 2 parts: what you finish before neuro, and then the 7 days themselves.

Finish the prerequisites and neuro stops being random. And during CNS, skip the ENT and ear pages.

Start here · before page 1

Neurology: micro and pharm first

Neuro starts with its own organisms and drugs: 31 organisms, the longest micro list of any system, and 4 drug groups (3 neuro groups plus the anaesthetics). Day 1 below does both, hour by hour. These are the full guides.

Microbiology Pharmacology
Where this system sits

The order: easy systems first, cardio last

Neurology is the 10th system of 11, right before cardio. MSK, psychiatry, genetics and ANS come first, and only cardio comes after it. Tap a system to open its guide.

  1. 1Renal6 days · the easy one, start hereOpen →
  2. 2Respiratory6 days · same method as renalOpen →
  3. Before it: Biochem nutrition, 1 day, right before GI · where it sits
  4. 3GI7 daysOpen →
  5. 4Reproductive7 daysOpen →
  6. Before it: Biochem carb and lipid metabolism, 1 day, right before endo · where it sits
  7. 5Endocrine6 daysOpen →
  8. 6Immunology5 daysOpen →
  9. Before it: Biochem cellular, molecular and amino acids, right before heme-onc · where it sits
  10. 7Heme-onc6 daysOpen →
  11. 8MSK6 days, no dermOpen →
  12. Before it: Dermatology, 3 days, after MSK · the derm block
  13. 9Psychiatry5 daysOpen →
  14. Before it: Genetics and ANS, right before neuro · genetics
  15. 10Neurology You are here7 daysOpen →
  16. 11Cardiovascular7 days · always lastOpen →

Biochem is never a block of its own: each piece sits right before the system that needs it. The whole method, once: how to study any system →

1

Before neuroDo genetics, MSK, psych and ANS first

It is highly recommended to do MSK, psych, ANS and genetics before neurology. On the USMLE Vault schedule they run in this order, right before neuro:

BeforeMSK6 days · its own page
BeforePsychiatry5 days · its own page
BeforeGeneticsBiochem pp. 54–62, active reading, 1 day
BeforeANSThe autonomic drugs, 1 day
▶Ninja Nerd · Autonomic Nervous SystemFor the ANS day. 31 minutes.
2

The planNeuro in 7 days, hour by hour

Once the 4 systems before it are done, neuro runs in the same fixed order as cardio. Here is every day, block by block.

Clock times assume an 11-hour day: 9 AM–1 PM, 2–6 PM and 7–10 PM, with lunch and dinner in the gaps. Shift the clock to your day. Keep the order. Day 2 and Day 3 start at 8 AM: neuro has the most pages of any system.

Day 1 · Micro + pharmThe longest Day 1 of any system
9–9:15 AMWatch How to do the CNS/Neurology system, the University walkthrough.
9:15 AM–1 PMMicro: the 11 bacteria and 11 viruses, WRWRT. Watch, recall, watch the gaps, read the Sketchy PDF.
2–5 PMMicro: the 5 parasites and 4 fungi. Then the First Aid Guide MCQs for all 31 organisms.
5–6 PMPharm: anticonvulsants and anti-parkinsonism drugs (Osmosis). Each video twice.
7–10 PMPharm: morphine and the opioids, then the general anaesthetics (Osmosis), twice. Read all 4 groups in the High-Yield Pharmacology PDF, highlight what didn't stick, then the neuro pharmacology MCQs.
Day 2 · Active readingFirst Aid Guide, page by page, MCQs on every page. 47 pages: the heaviest reading day of any system
8 AM–1 PMpp. 500–515 · neural development, nerve cells, neurotransmitters, meninges, sleep, hypothalamus, limbic system, cerebellum, basal ganglia, cortex, cerebral arteries, ventricles
2–6 PMpp. 516–530 · brainstem, cranial nerves, spinal tracts, reflexes, dermatomes, brain lesions, stroke, haemorrhage, aphasia, aneurysms
7–10 PMpp. 531–546 · seizures, headaches, movement disorders, dementia, hydrocephalus, MS, neurocutaneous disorders, tumours, herniation, UMN vs LMN, cord and cranial nerve lesions
Day 3 · Reading, then MehlmanSkip pp. 547–548 (ear) today
8 AM–1 PMpp. 549–569 · the eye, pupils, cranial nerve palsies, visual fields, then the neuro drugs and anaesthetics
2–6 PMWatch How to watch Mehlman Medical videos (10 minutes), then the Mehlman neuro playlist from the top, in order.
7–10 PMMehlman, continued. Pause before he answers and answer it yourself.
Day 4 · Mehlman, then Anki
9 AM–1 PMFinish the Mehlman neuro playlist. Any gap → that First Aid Guide page, the same day.
2–6 PMFA Foundation Anki · CNS, 267 cards. Answer before you flip.
7–9 PMFinish the deck. Then open the First Aid page of every card you hesitated on.
Day 5 · UWorld neuroUnused · neurology only · tutor mode · 20 questions a block
9–9:30 AMClear today's due FA Foundation Anki cards first.
9:30 AM–1 PMBlocks 1–2 (Qs 1–40): solve both in tutor mode, log each score, then review every bookmark in First Aid.
2–6 PMBlocks 3–4 (Qs 41–80): solve both in tutor mode, log each score, then review every bookmark in First Aid.
7–10 PMBlocks 5–6 (Qs 81–120): solve both in tutor mode, log each score, then review every bookmark in First Aid.
Day 6 · UWorld neuro
9–9:30 AMClear today's due FA Foundation Anki cards first.
9:30 AM–1 PMBlocks 7–8 (Qs 121–160): solve both in tutor mode, log each score, then review every bookmark in First Aid.
2–6 PMBlocks 9–10 (Qs 161–200): solve both in tutor mode, log each score, then review every bookmark in First Aid.
7–10 PMBlocks 11–12 (Qs 201–240): solve both in tutor mode, log each score, then review every bookmark in First Aid.
Day 7 · UWorld neuro + Anki revisionBlocks 19–20 go to the next morning
9–9:30 AMClear today's due FA Foundation Anki cards first.
9:30 AM–1 PMBlocks 13–14 (Qs 241–280): solve both in tutor mode, log each score, then review every bookmark in First Aid.
2–6 PMBlocks 15–16 (Qs 281–320): solve both in tutor mode, log each score, then review every bookmark in First Aid.
7–10 PMBlocks 17–18 (Qs 321–360): solve both in tutor mode, log each score, then review every bookmark in First Aid.
Same pages, 5 angles. Micro and pharm, then active reading, then active application, then active recall, then UWorld. Every step hits the same 68 First Aid pages from a different direction. The method behind every system →

Want a day-by-day schedule that tells you exactly what to study next? The Vault builds it around your exam date.

USMLE Vault day-by-day schedule Build my schedule →
3

Day 1Micro and pharm of neuro, from the pills

Open the First Aid Guide → Neurology in the Vault (what the First Aid Guide is) and use the Micro and Pharm pills. Neuro has the longest micro list of any system, so start the micro early in the day.

Neurology in the First Aid Guide on usmlevault.com: its First Aid pages, MCQ count, the micro and pharm pills it has, and the How to do Neurology video.
Neurology in the First Aid Guide on usmlevault.com: its First Aid pages, MCQ count, the micro and pharm pills it has, and the How to do Neurology video.

Micro · 31 organisms · the WRWRT method. Watch the sketch at 1x with no notes → Recall the whole story in your head, in order → Watch again only the gaps at 1.5–1.75x → Read the Sketchy PDF for that organism → Test with the First Aid Guide MCQs for that organism.

Bacteria · 11N. meningitidisS. pneumoniaeH. influenzae type BListeriaGroup B strepE. coli K1M. tuberculosisT. pallidum (neurosyphilis)B. burgdorferiC. botulinumC. tetaniViruses · 11HSVVZVCMVEBVHHV-6RabiesEnterovirusesMumpsMeasles (SSPE)West NileJC virus (PML)Parasites · 5ToxoplasmaNaegleria fowleriAcanthamoebaT. bruceiTaenia solium (neurocysticercosis)Fungi · 4CryptococcusCoccidioidesHistoplasmaBlastomyces

Open Neuro Micro → · The Sketchy Micro guide →

▶How to do Sketchy MicroThe efficient method, 15 minutes.

Pharm · the FWRT method. Find the resource (already mapped for you, below) → Watch each video twice, back to back → Read the High-Yield Pharmacology PDF after all of them, and highlight only what did not survive → Test in the First Aid Guide → Neuro → Pharmacology.

"Doing the pharmacology section from videos is extremely important. It will take you half a day, 5 to 6 hours, to understand them."

Open Anaesthesia Pharm →

Open Neuro Pharm → · The full pharm map →

▶How to complete pharmacologyThe high-yield pharm strategy, 15 minutes.
Never done Sketchy? Do the same list from First Aid and the First Aid Guide alone. The list does not change, only the source. Every system's micro and pharm →
Why micro and pharm first: when you reach meningitis, encephalitis and the brain abscesses, and the anticonvulsants on pp. 560–561, you meet them as old friends, not new facts.
4

Before Day 2What the First Aid Guide is, and why you read it

First Aid was written to remind you, not to teach you. Every line assumes you already understand it. That is why IMGs spend 3 hours on 1 page, Google half of it, and still remember nothing a week later.

The First Aid Guide on usmlevault.com puts the teaching back into the page. Every neurology page (pp. 500–569) has the same 5 parts:

Example: p. 525, Ischemic brain disease and stroke.

Focus On tells you what matters on this page: the 3 types of ischemic stroke (thrombotic, embolic, hypoxic), the timeline of histologic changes, treatment windows, and the types of cerebral edema. That page already carries Dirty Medicine's "Strokes & The Rule of 4s" among its videos.

First Aid p. 525 (Ischemic brain disease and stroke) in the First Aid Guide: Focus On, the ELI5s, the video guide, Concept walkthrough, Key takeaways, How is this tested? and Test yourself.
First Aid p. 525 (Ischemic brain disease and stroke) in the First Aid Guide: Focus On, the ELI5s, the video guide, Concept walkthrough, Key takeaways, How is this tested? and Test yourself.
Why it works: you understand the page, then prove it with MCQs in the same minute. 60–70% of UWorld traces straight back to First Aid lines, so a page you truly understood is a UWorld question you already own.

Open Neurology in the First Aid GuideFirst Aid pp. 500–569, page by page: Focus On, ELI5 and the MCQs on every page. Opens straight into neurology.

Open Neurology →
▶How to use the First Aid GuideWatch once, before your first page.
5

Day 2 → Day 3 morningActive reading: First Aid pp. 500–569, ear pages skipped

Active reading means that for every page you explain it, understand it, and do it. The MCQs are part of the reading. That is what makes it active. You do not move to the next page until all 3 are done.

  1. Read Focus On for the page. Now you know what matters.
  2. Run the Concept Walkthrough and the ELI5s. Explain each heading back in your own words, out loud. If you cannot say it, you have not understood it.
  3. Read the actual First Aid page. It should now read like a summary of something you already know.
  4. Solve the Test Yourself MCQs. Any miss → back to that heading before you turn the page.
Pace: 10–12 minutes a page, 4–6 pages an hour. Do not memorise. Understanding is the only job on these pages. Memory is the Anki step's job.
Skip the ENT and ear pages during CNS: pp. 547–548 (ear anatomy, otitis, hearing loss, vertigo). They are crossed out below.
Day 2 · pp. 500–546 · embryology to cranial nerve lesions (47 pages)
500–502Neural development, neural tube defects, posterior fossa malformations
503–509Nerve cells, action potential, neurotransmitters, meninges, BBB, sleep, hypothalamus, limbic system
510–515Cerebellum, basal ganglia, cortex, homunculus, cerebral arteries, circle of Willis, ventricles
516–523Brainstem, cranial nerves, spinal cord tracts, reflexes, dermatomes
524–530Brain lesions, stroke by artery, haemorrhage, aphasia, aneurysms
531–539Seizures, headaches, movement disorders, dementia, hydrocephalus, MS, neurocutaneous disorders
540–546Brain tumours, herniation, UMN vs LMN, spinal cord lesions, cranial nerve lesions
Day 3 morning · pp. 549–569 (21 pages)
549–553Eye anatomy, refractive errors, lens, glaucoma, retina, papilledema, uveitis
554–559Pupils, Horner syndrome, CN III, IV and VI palsies, visual fields, INO, eyelids
560–564Anticonvulsants, barbiturates, benzodiazepines, triptans, Parkinson drugs
565–569Anaesthetics, neuromuscular blockers, muscle relaxants, opioids, glaucoma drugs
Day 2 is the heaviest reading day of any system: 47 pages. At 10–12 minutes a page that is 8–9 hours. Start it early.
6

Day 3 afternoon → Day 4 morningActive application: Mehlman Medical

You understand neuro. Now you learn how the exam asks it. Mehlman's videos take each high-yield topic and show you which clue rules an answer in, which one rules it out, and how to get from the stem to the answer.

  1. Videos, not PDFs. The value is the reasoning, and the PDFs do not have it.
  2. The full neuro playlist, in order. Not random clips. Watch the how-to video below first.
  3. Pause before he answers, and answer it yourself. Anything that exposes a gap → open that First Aid Guide page and fix it the same day.
  4. Short on time? Sort the playlist by date and watch the last 3 years first.
▶Mehlman Medical · Neuro playlistWatch in order. This is the step. ▶How to watch Mehlman Medical videosWatch this before the playlist, 10 minutes.
Why: active reading gave you the facts. Active application turns facts into decisions, and a decision is the only thing a UWorld question asks for. How to use Mehlman →
7

Day 4 afternoonActive recall: FA Foundation Anki

What it is: the FA Foundation Anki deck is First Aid, page by page. 1 high-yield point per card, and the First Aid page number is on every card. The Neurology deck is 267 cards (as of October 2026).

How to use it: run the whole neuro deck in this half day. Answer before you flip. If you hesitate, open that page in the First Aid Guide, read the line plus a couple of lines above and below, then go back to the card.

Why: this is your third full pass of neuro First Aid, and the first one done without the page in front of you. Recognising a line and pulling it out of memory are different skills, and UWorld tests the second one.

Example card · FA Foundation Anki · NeurologyA patient dies 5 days after a large ischemic stroke. The neuropathologist examines the infarcted tissue.
Which cell type predominates at this time point, and what was the predominant cell 2 days earlier?
Macrophages and microglia predominate at days 3–7. At days 2–3, neutrophils were the dominant cells.
First Aid p. 525
▶How to do Anki from the First Aid GuideHow to run the FA Foundation Anki cards, 10 minutes.

On the UWorld days, keep the deck running: clear the cards that are due before your first block each morning. How to run the decks → · Open FA Foundation Anki in the Vault →

Run the FA Foundation Anki · Neurology deck267 cards (as of October 2026), First Aid page by page, with the page number on every card. Opens straight into the deck.

Open the deck →
8

Days 5–7UWorld neuro: the RPSR method

Now you open UWorld. You are not meeting neuro here. You are proving you already own it.

UWorld settings
QuestionsUnused
SubjectsAll
SystemsNeurology only
ModeTutor, untimed
Block20 questions
  1. Solve. Do 2 blocks of 20. Bookmark every question you got wrong and every one you got right by guessing.
  2. Review in First Aid. For each bookmark, find the exact First Aid line it came from, highlight it, and read a couple of lines around it. 5–6 minutes a question, no more. Then the next 2 blocks.
Target: 65% or above. If your last 2 blocks are under 60%, go back to the Mehlman videos for those topics, then the First Aid pages behind them.

Neurology has about 400 UWorld questions on the USMLE Vault schedule. That is the most of any system. At 9 minutes a question for solving and review, it is about 60 hours, so Days 5–7 start them and UWorld neuro will run past Day 7. Keep going until the 3 checks below are true.

Neurology is finished when every neuro UWorld question is attempted, every miss is traced to its First Aid page, and your last 2 blocks held above 65%. Not when a date passes. When is a system actually finished? →

Later, for your NBMEs: NBME Booster Anki · NeurologyThe neurology questions from retired NBME forms 20 to 34 and the Free 120, as cards. Not for now: open it when your NBME phase starts. What the Booster is →

Open the Booster deck →
▶How to solve UWorld and Amboss questionsWatch before your first block, 20 minutes.

The full method: The RPSR Method →

What not to do

Do not open UWorld on Day 1. You will score 40%, decide you are bad at neuro, and you are simply in the wrong order.
Do not read First Aid to memorise it. The reading days are for understanding. Memory is the Anki step's job.
Do not skip the page MCQs. If you cannot answer them, you read the page. You did not learn it.
Do not split neuro across weeks. 7 days in a row. A half-done system behaves like an undone one.
Do not start neuro before ANS and genetics. You will spend Day 2 learning neurotransmitters and inheritance instead of neurology.
Let the schedule place neuro, and everything before it.
The schedule puts MSK, psych, genetics and ANS in front of neuro for you, with the right pages on each day.
Open usmlevault.com/schedule →
usmlevault.com · Renal is free · free for your first 3 days
Read next

Cardiovascular in 7 days — the same method, step by step.

MSK in 6 days — the first of the 4 systems before neuro.

Psychiatry in 5 days — the second.

Biochemistry — where genetics and every other biochem piece sits.

How to study any system — the method every system page uses.

The RPSR Method — how to solve and review UWorld.

When is a system actually finished? — the checks before you move on.

USMLE Vault · Neurology, start to finish, in 7 days · Created 2026-10-22 · All free guides
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